If winning La Liga caused Atletico Madrid to soften their edge or lose their identity, a Champions League tie against Manchester United could be a chance for them to get it back.
Sebastien Haller will be bidding to continue his remarkable scoring record in this season's Champions League when his Ajax side face Benfica in the first leg of their last-16 tie on Wednesday.
David de Gea returns to the city of his birth and club where he grew up on Wednesday as Manchester United head to Atletico Madrid in a Champions League clash between two giants that have fallen on hard times.
Ralf Rangnick said Manchester United's fightback from blowing another half-time lead to beat Leeds 4-2 was the "best possible response" his side could give to reports of dressing room unrest.
Thomas Tuchel admits Chelsea are fighting to "survive" as the spluttering Champions League holders prepare to face Lille in the last 16 first leg on Tuesday.
There may be a Premier League title race after all as a Harry Kane-inspired Tottenham ended Manchester City's unbeaten run stretching back to October, while Liverpool kept up their chase of the leaders by seeing off Norwich.
Pierre-Emerick Aubameyang said Valencia's Mestalla stadium feels like home after he scored a hat-trick in Barcelona's 4-1 victory on Sunday.
Super subs Fred and Anthony Elanga stepped off the bench to fire Manchester United to a 4-2 win over Leeds United in a classic at Elland Road.
Mikel Arteta refused to get carried away in the race for the Premier League top four after Arsenal beat Brentford as he admitted losing the reverse fixture had left a “scar” on his side.
Harry Kane and Son Heung-min have had a remarkable understanding ever since they first became Tottenham teammates and against Manchester City on Saturday they etched their names into Premier League history.