Orlando Pirates will be without Oupa Manyisa and Luvuyo Memela when they take on SuperSport United at the Mbombela Stadium on Tuesday.
Both Manyisa and Memela are still recovering from a severe case of stomach cramps after having missed the Soweto derby against Kaizer Chiefs, according to the Orlando Pirates website.
Meanwhile, the Sea Robbers medical department has stated some players are making good progress from their respective injuries.
Buccaneers duo Gladwin Shitolo and Nkosinathi Mthiyane have been given the all clear to resume training with the first team.
Striker Ayanda Nkosi is still receiving rehabilitation treatment for a hamstring strain and is expected to return to full training in a couple of days.
Meanwhile, Bucs shot-stopper Siyabonga Mpontshane is on an individual biokinetic training programme and making good progress.
Orlando Pirates will next take on SuperSport United in the Absa Premiership on Tuesday.
The match at Mbombela Stadium kicks off at 19:30.