Moussa Sow scored an audacious second minute goal to set Fenerbahce on the path to a famous win over Manchester United on Thursday.

Struggling for Premier League form, United manager Jose Mourinho opted to start Wayne Rooney as his sole striker with Ander Herrera playing just behind him in the Europa League clash in Turkey.

Mourinho’s team selection mattered for little when Senegal striker Sow struck an acrobatic effort from the edge of the area which left David De Gea no chance as the hosts went in front.

The Red Devils seized control of the match but created little in the way of chances and were dealt another blow when Paul Pogba limped off following a heavy challenge which leaves him doubt to start against Swansea on Sunday.

The visitors upped the tempo but ultimately failed to get onto the scoresheet as the half time whistle sounded, a worrying sign after the goalless draw against Burnley.

The second half was a much more even contest in terms of possession and United were lucky not concede more with Emmanuel Emenike failing to take advantage of two clear cut chances.

Sunderland loanee Jermain Lens made it 2-0 when he beat the wall and left De Gea rooted to his goalline. The goal sent the partison home crowd into hysterics as they felt even more convinced of a historic European night.

Wayne Rooney set up a nervy finish when he scored with a long range thunderbolt in only the second of his side’s shot on target. He almost equalised with a minute left on the clock but his looping header from Juan Mata’s corner was cleared off the line.

The hosts held on under intense pressure for a win which saw them leapfrog United on the table into second with the English giants now in third with two games to play.